Endocrine Abstracts

Fibroblast growth factor-21 (FGF-21) is a novel adipocytokine, which is believed to be involved in improvement of insulin sensitivity and pathogenesis of type 2 diabetes.The aim of the study was comparative assessment of FGF-21 concentrations in serum of patients with type 2 diabetes and evaluation of possible relationships between the studied cytokine and selected clinical and biochemical parameters.Forty-four patients with type 2...

Introduction: It’s known that type 2 diabetes is an independent risk factor for cardiovascular disease. Osteoprotegerin (OPG), a glycoprotein secreted mainly by osteoblasts, is also produced by heart muscle and vessels. Its role in the pathogenesis of atherosclerosis and future cardiovascular events is still discussed.Material and methods: The study was conducted in 113 patients (48 F, 65 M) with type 2 diabetes mellitus (DM2) and coronary heart dis...